Stroke volume and regional stroke volume in 2 mm sagital slices used for the biochemical assays were analyzed using Analyze 5.0 and Image J software. The left hippocampus sparing was higher with IMRT. TAT.ARC protein administration in the contralateral ventricle decreased lesion volume in subregions of the ischemic territory after 24 h and 72 h after 60 min middle cerebral artery occlusion. The Willis' circle was better protected with PBS-PT than IMRT (-7.1% -7.8%). Compared to IMRT and VMAT, PBS-PT showed statistically significant optimized IC, as well as dose reduction, among others, in mean and integral dose to the: normal brain (-35.2%, -32.7% -35.2%, -33.0%, respectively), cerebellum (-53.7%, -33.1% -53.6%, -32.7%) and right temporal lobe (-14.5%, -31.9% -14.7%, -29.9%). TVC was comparable for all three modalities. Cardiac sparing 4-dimensional-based intensity modulated radiation therapy (IMRT) plan showing 95 isodose line (blue), 75 (green line), and 50 (yellow line) on CT images of left ventricle (red), right ventricle (light blue), and whole lung planning target volume (purple).
NOAR were delineated and treatment plans were compared for target volume coverage (TVC), homogeneity index (HI), inhomogeneity coefficient (IC) and (N)OAR sparing. Download : Download high-res image (260KB) Download : Download full-size image Fig. Intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) plans were generated for these patients. Link/Page Citation Category Filters All definitions (7) Information Technology (1) Military & Government (2) Science & Medicine (2) Organizations, Schools, etc. showing only Information Technology definitions. Therefore, a dosimetric comparison study of WV-RT/TB was conducted to assess whether proton or photon radiotherapy achieves better NOAR sparing.Įleven children with GCT received 24 Gy(RBE) WV-RT and a boost up to 40 Gy(RBE) in 25 fractions of 1.6 Gy(RBE) with pencil beam scanning proton therapy (PBS-PT). What does QARC stand for Your abbreviation search returned 7 meanings. As the critical brain areas are mainly in the target volume vicinity, it is unclear if protons indeed substantially spare neurofunctional organs at risk (NOAR). Whole-ventricular radiotherapy (WV-RT) followed by a boost to the tumor bed (WV-RT/TB) is recommended for intracranial germ cell tumors (IGCT).